HBV Target gene Detail Information

> PTH2R Gene Search Result

Gene Information

Gene Name	PTH2R
Gene ID	5746
Gene Full Name	parathyroid hormone 2 receptor
Gene Alias	PTHR2
Transcripts	ENSG00000144407
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins
Uniport_ID	P49190
HGNC ID	HGNC:9609
VEGA ID	OTTHUMG00000132960
OMIM ID	601469
String ID	9606.ENSP00000272847
Drugbank ID	BE0004703
PharmGKB ID	PA162400333

Target gene [PTH2R] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000615	chr2	1405	167	217	1789	View
1402817	chr2	1405	167	217	1789	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PTH2R expression and immune infiltrating cell level correlation result in HBV+ samples
PTH2R expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).