HIV Target gene Detail Information

> PTGER3 Gene Search Result

Gene Information

Gene Name	PTGER3
Gene ID	5733
Gene Full Name	prostaglandin E receptor 3
Gene Alias	EP3; EP3e; EP3-I; EP3-II; EP3-IV; EP3-VI; PGE2-R; EP3-III
Transcripts	ENSG00000050628
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins
Uniport_ID	P43115
HGNC ID	HGNC:9595
VEGA ID	OTTHUMG00000009399
OMIM ID	176806
String ID	9606.ENSP00000349003
Drugbank ID	BE0002375
PharmGKB ID	PA288

Target gene [PTGER3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011671	chr1	6			6	View
4013132	chr1	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PTGER3 expression and immune infiltrating cell level correlation result in HIV+ samples
PTGER3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).