HIV Target gene Detail Information

> PTDSS1 Gene Search Result

Gene Information

Gene Name	PTDSS1
Gene ID	9791
Gene Full Name	phosphatidylserine synthase 1
Gene Alias	LMHD; PSS1; PSSA
Transcripts	ENSG00000156471
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins
Uniport_ID	P48651
HGNC ID	HGNC:9587
VEGA ID	OTTHUMG00000164687
OMIM ID	612792
String ID	9606.ENSP00000430548
Drugbank ID	BE0001099
PharmGKB ID	PA33939

Target gene [PTDSS1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003705	chr8	12	25	19	56	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PTDSS1 expression and immune infiltrating cell level correlation result in HIV+ samples
PTDSS1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PTDSS1 expression and immune infiltrating cell level correlation result in HIV+ samples
PTDSS1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).