HIV Target gene Detail Information

> PTBP1 Gene Search Result

Gene Information

Gene Name	PTBP1
Gene ID	5725
Gene Full Name	polypyrimidine tract binding protein 1
Gene Alias	PTB; PTB2; PTB3; PTB4; pPTB; HNRPI; PTB-1; PTB-T; HNRNPI; HNRNP-I
Transcripts	ENSG00000011304
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	P26599
HGNC ID	HGNC:9583
VEGA ID	OTTHUMG00000181789
OMIM ID	600693
String ID	9606.ENSP00000349428
PharmGKB ID	PA33934

Target gene [PTBP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003376	chr19	50	13		63	View
4004443	chr19	38	5	1	44	View
4004708	chr19	35	4	1	40	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PTBP1 expression and immune infiltrating cell level correlation result in HIV+ samples
PTBP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PTBP1 expression and immune infiltrating cell level correlation result in HIV+ samples
PTBP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).