Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> PTAFR Gene Search Result


Gene Information
Gene Name PTAFR
Gene ID 5724
Gene Full Name platelet activating factor receptor
Gene Alias PAFR
Transcripts ENSG00000169403
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Vesicles;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters
Uniport_ID P25105
HGNC ID HGNC:9582
VEGA ID OTTHUMG00000003953
OMIM ID 173393
String ID 9606.ENSP00000362965
Drugbank ID BE0005489; BE0005561
PharmGKB ID PA33933
Target gene [PTAFR] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008014 chr1 14 8 1 23 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of PTAFR expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
PTAFR expression: Low -> High
Lollipop of PTAFR expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of PTAFR expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PTAFR expression and immune infiltrating cell level correlation result in HBV+ samples
PTAFR expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).