HTLV1 Target gene Detail Information

> PSTPIP1 Gene Search Result

Gene Information

Gene Name	PSTPIP1
Gene ID	9051
Gene Full Name	proline-serine-threonine phosphatase interacting protein 1
Gene Alias	H-PIP; PAPAS; CD2BP1; PSTPIP; CD2BP1L; CD2BP1S
Transcripts	ENSG00000140368
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	O43586
HGNC ID	HGNC:9580
VEGA ID	OTTHUMG00000172594
OMIM ID	606347
String ID	9606.ENSP00000452746
PharmGKB ID	PA33931

Target gene [PSTPIP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001053	chr15	138	258	219	615	View
6001473	chr15	231	76	115	422	View
6019185	chr15	8			8	View
6022566	chr15	4	1		5	View
6028989	chr15	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PSTPIP1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PSTPIP1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PSTPIP1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PSTPIP1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of PSTPIP1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PSTPIP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).