HIV Target gene Detail Information

> PSMD12 Gene Search Result

Gene Information

Gene Name	PSMD12
Gene ID	5718
Gene Full Name	proteasome 26S subunit, non-ATPase 12
Gene Alias	p55; Rpn5; STISS
Transcripts	ENSG00000197170
Virus	HIV
Gene Type	protein coding
HPA Location Info	Microtubules;Cytosol;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	O00232
HGNC ID	HGNC:9557
VEGA ID	OTTHUMG00000140376
OMIM ID	604450
String ID	9606.ENSP00000348442
PharmGKB ID	PA33903

Target gene [PSMD12] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000357	chr17	109	147	264	520	View
4000371	chr17	68	148	292	508	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PSMD12 expression and immune infiltrating cell level correlation result in HIV+ samples
PSMD12 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PSMD12 expression and immune infiltrating cell level correlation result in HIV+ samples
PSMD12 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).