HIV Target gene Detail Information

> PSMB9 Gene Search Result

Gene Information

Gene Name	PSMB9
Gene ID	5698
Gene Full Name	proteasome subunit beta 9
Gene Alias	LMP2; PRAAS3; PSMB6i; RING12; beta1i
Transcripts	ENSG00000243958
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P28065
HGNC ID	HGNC:9546
VEGA ID	OTTHUMG00000012781
OMIM ID	177045
String ID	9606.ENSP00000363993
Drugbank ID	BE0004737
PharmGKB ID	PA33891

Target gene [PSMB9] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002312	chr6	82	18		100	View
4007276	chr6	19	1		20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PSMB9 expression and immune infiltrating cell level correlation result in HIV+ samples
PSMB9 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PSMB9 expression and immune infiltrating cell level correlation result in HIV+ samples
PSMB9 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).