HIV Target gene Detail Information

> PSMB3 Gene Search Result

Gene Information

Gene Name	PSMB3
Gene ID	5691
Gene Full Name	proteasome subunit beta 3
Gene Alias	HC10-II
Transcripts	ENSG00000275903
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P49720
HGNC ID	HGNC:9540
VEGA ID	OTTHUMG00000191277
OMIM ID	602176
String ID	9606.ENSP00000483688
Drugbank ID	BE0003917
PharmGKB ID	PA33885

Target gene [PSMB3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006189	chr17	16	10		26	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PSMB3 expression and immune infiltrating cell level correlation result in HIV+ samples
PSMB3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PSMB3 expression and immune infiltrating cell level correlation result in HIV+ samples
PSMB3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).