HIV Target gene Detail Information

> PSIP1 Gene Search Result


Gene Information
Gene Name PSIP1
Gene ID 11168
Gene Full Name PC4 and SFRS1 interacting protein 1
Gene Alias p52; p75; PAIP; DFS70; LEDGF; PSIP2
Transcripts ENSG00000164985
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID O75475
HGNC ID HGNC:9527
VEGA ID OTTHUMG00000021021
OMIM ID 603620
String ID 9606.ENSP00000370109
PharmGKB ID PA33872
Target gene [PSIP1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4009170 chr9 10 2 12 View
4013125 chr9 4 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PSIP1 expression and immune infiltrating cell level correlation result in HIV+ samples
PSIP1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of PSIP1 expression and immune infiltrating cell level correlation result in HIV+ samples
PSIP1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).