HBV Target gene Detail Information

> PRUNE2 Gene Search Result

Gene Information

Gene Name	PRUNE2
Gene ID	158471
Gene Full Name	prune homolog 2
Gene Alias	BMCC1; BNIPXL; C9orf65; KIAA0367
Transcripts	ENSG00000106772
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8WUY3
HGNC ID	HGNC:25209
VEGA ID	OTTHUMG00000020047
OMIM ID	610691
String ID	9606.ENSP00000365908
PharmGKB ID	PA162400198

Target gene [PRUNE2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005332	chr9	7	47	2	56	View
1400123	chr9	1472	143	47	1662	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PRUNE2 expression and immune infiltrating cell level correlation result in HBV+ samples
PRUNE2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).