HBV Target gene Detail Information

> PRSS53 Gene Search Result

Gene Information

Gene Name	PRSS53
Gene ID	339105
Gene Full Name	serine protease 53
Gene Alias	POL3S; UNQ308
Transcripts	ENSG00000151006
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted secreted proteins
Uniport_ID	Q2L4Q9
HGNC ID	HGNC:34407
VEGA ID	OTTHUMG00000047358
OMIM ID	610561
String ID	9606.ENSP00000280606
PharmGKB ID	PA165450635

Target gene [PRSS53] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005564	chr16	13	10	29	52	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PRSS53 expression and immune infiltrating cell level correlation result in HBV+ samples
PRSS53 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).