HBV Target gene Detail Information

> PRSS50 Gene Search Result

Gene Information

Gene Name	PRSS50
Gene ID	29122
Gene Full Name	serine protease 50
Gene Alias	CT20; TSP50
Transcripts	ENSG00000283706
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q9UI38
HGNC ID	HGNC:17910
VEGA ID	OTTHUMG00000164067
OMIM ID	607950
String ID	9606.ENSP00000418875
PharmGKB ID	PA165698443

Target gene [PRSS50] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001975	chr3	238	109	42	389	View
1002594	chr3	225	14	2	241	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PRSS50 expression and immune infiltrating cell level correlation result in HBV+ samples
PRSS50 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).