HBV Target gene Detail Information

> PRSS12 Gene Search Result

Gene Information

Gene Name	PRSS12
Gene ID	8492
Gene Full Name	serine protease 12
Gene Alias	MRT1; BSSP3; BSSP-3
Transcripts	ENSG00000164099
Virus	HBV
Gene Type	protein coding
HPA Location Info	Actin filaments;Nucleoplasm;Predicted to be secreted;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins
Uniport_ID	P56730
HGNC ID	HGNC:9477
VEGA ID	OTTHUMG00000161166
OMIM ID	606709
String ID	9606.ENSP00000296498
PharmGKB ID	PA33830

Target gene [PRSS12] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1012978	chr4	4		2	6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PRSS12 expression and immune infiltrating cell level correlation result in HBV+ samples
PRSS12 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).