HIV Target gene Detail Information

> PRRC2A Gene Search Result


Gene Information
Gene Name PRRC2A
Gene ID 7916
Gene Full Name proline rich coiled-coil 2A
Gene Alias G2; BAT2; D6S51; D6S51E
Transcripts ENSG00000231370
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P48634
HGNC ID HGNC:13918
VEGA ID OTTHUMG00000004895
OMIM ID 142580
String ID 9606.ENSP00000365201
PharmGKB ID PA25263
Target gene [PRRC2A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002172 chr6 107 1 108 View
4005400 chr6 32 1 33 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PRRC2A expression and immune infiltrating cell level correlation result in HIV+ samples
PRRC2A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).