HIV Target gene Detail Information

> PRPF4B Gene Search Result

Gene Information

Gene Name	PRPF4B
Gene ID	8899
Gene Full Name	pre-mRNA processing factor 4B
Gene Alias	PR4H; PRP4; PRP4H; PRP4K; dJ1013A10.1
Transcripts	ENSG00000112739
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q13523
HGNC ID	HGNC:17346
VEGA ID	OTTHUMG00000014157
OMIM ID	602338
String ID	9606.ENSP00000337194
Drugbank ID	BE0009481; BE0009527
PharmGKB ID	PA38447

Target gene [PRPF4B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4014510	chr6		2		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PRPF4B expression and immune infiltrating cell level correlation result in HIV+ samples
PRPF4B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PRPF4B expression and immune infiltrating cell level correlation result in HIV+ samples
PRPF4B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).