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HBV Target gene Detail Information

> PRPF31 Gene Search Result


Gene Information
Gene Name PRPF31
Gene ID 26121
Gene Full Name pre-mRNA processing factor 31
Gene Alias RP11; PRP31; SNRNP61; NY-BR-99
Transcripts ENSG00000274894
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q8WWY3
HGNC ID HGNC:15446
VEGA ID OTTHUMG00000189021
OMIM ID 606419
String ID 9606.ENSP00000324122
PharmGKB ID PA33814
Target gene [PRPF31] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000158 chr4 2007 1706 1424 5137 View
1000983 chr7 30 652 516 1198 View
1001084 chr16 530 349 214 1093 View
1001716 chr3 27 398 91 516 View
1003402 chr9 105 1 30 136 View
1004552 chr12 43 26 8 77 View
1004772 chr3 2 28 39 69 View
1004781 chr4 2 23 44 69 View
1005264 chr9 52 4 1 57 View
1005369 chr12 33 21 2 56 View
1006653 chr5 19 14 2 35 View
1007266 chr10 8 17 3 28 View
1007356 chr4 14 7 7 28 View
1008223 chr12 14 6 2 22 View
1008508 chr18 19 1 20 View
1008686 chr8 16 3 19 View
1010885 chr8 10 10 View
1012018 chr14 7 1 8 View
1012570 chr18 3 3 6 View
1012953 chr5 1 5 6 View
1012954 chr5 2 4 6 View
1012955 chr6 6 6 View
1013130 chr12 2 3 5 View
1014342 chr4 1 2 3 View
1014349 chr11 2 1 3 View
1015245 chr17 1 1 2 View
1015323 chr18 2 2 View
1016022 chr13 1 1 2 View
1016151 chr4 1 1 View
1016159 chr4 1 1 View
1016169 chr14 1 1 View
1016341 chr1 1 1 View
1016349 chr18 1 1 View
1017346 chr10 1 1 View
1017520 chr4 0 View
1017879 chr4 0 View
1019710 chr15 0 View
1019721 chr10 0 View
1019722 chr10 0 View
1019732 chr8 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of PRPF31 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
PRPF31 expression: Low -> High
Lollipop of PRPF31 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of PRPF31 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PRPF31 expression and immune infiltrating cell level correlation result in HBV+ samples
PRPF31 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).