HIV Target gene Detail Information

> PRPF3 Gene Search Result


Gene Information
Gene Name PRPF3
Gene ID 9129
Gene Full Name pre-mRNA processing factor 3
Gene Alias PRP3; RP18; HPRP3; Prp3p; HPRP3P; SNRNP90
Transcripts ENSG00000117360
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID O43395
HGNC ID HGNC:17348
VEGA ID OTTHUMG00000012807
OMIM ID 607301
String ID 9606.ENSP00000315379
PharmGKB ID PA134892509
Target gene [PRPF3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4008109 chr1 14 2 16 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PRPF3 expression and immune infiltrating cell level correlation result in HIV+ samples
PRPF3 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of PRPF3 expression and immune infiltrating cell level correlation result in HIV+ samples
PRPF3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).