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HTLV1 Target gene Detail Information

> PROZ Gene Search Result


Gene Information
Gene Name PROZ
Gene ID 8858
Gene Full Name protein Z, vitamin K dependent plasma glycoprotein
Gene Alias PZ
Transcripts ENSG00000126231
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins
Uniport_ID P22891
HGNC ID HGNC:9460
VEGA ID OTTHUMG00000017376
OMIM ID 176895
String ID 9606.ENSP00000344458
PharmGKB ID PA33813
Target gene [PROZ] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6016076 chr13 10 3 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of PROZ expression and immune infiltrating cell level correlation result in HTLV1+ samples
PROZ expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of PROZ expression and immune infiltrating cell level correlation result in HTLV1+ samples
PROZ expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of PROZ expression and immune infiltrating cell level correlation result in HTLV1+ samples
PROZ expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).