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HBV Target gene Detail Information

> PROS1 Gene Search Result


Gene Information
Gene Name PROS1
Gene ID 5627
Gene Full Name protein S
Gene Alias PSA; PROS; PS21; PS22; PS23; PS24; PS25; THPH5; THPH6
Transcripts ENSG00000184500
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID P07225
HGNC ID HGNC:9456
VEGA ID OTTHUMG00000150354
OMIM ID 176880
String ID 9606.ENSP00000377783
Drugbank ID BE0000943
PharmGKB ID PA33809
FDA Approved Drug Avatrombopag;Estradiol;Progesterone;Lusutrombopag;Synthetic Conjugated Estrogens,A;Warfarin
Target gene [PROS1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009816 chr3 14 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PROS1 expression and immune infiltrating cell level correlation result in HBV+ samples
PROS1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).