HBV Target gene Detail Information

> PROM1 Gene Search Result


Gene Information
Gene Name PROM1
Gene ID 8842
Gene Full Name prominin 1
Gene Alias RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061
Transcripts ENSG00000007062
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID O43490
HGNC ID HGNC:9454
VEGA ID OTTHUMG00000160180
OMIM ID 604365
String ID 9606.ENSP00000426809
PharmGKB ID PA33807
Target gene [PROM1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008520 chr4 19 1 20 View
1011692 chr4 6 2 8 View
1400536 chr4 13 138 2 153 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PROM1 expression and immune infiltrating cell level correlation result in HBV+ samples
PROM1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).