HIV Target gene Detail Information

> PRMT2 Gene Search Result

Gene Information

Gene Name	PRMT2
Gene ID	3275
Gene Full Name	protein arginine methyltransferase 2
Gene Alias	HRMT1L1
Transcripts	ENSG00000160310
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	P55345
HGNC ID	HGNC:5186
VEGA ID	OTTHUMG00000048806
OMIM ID	601961
String ID	9606.ENSP00000380759
PharmGKB ID	PA29460

Target gene [PRMT2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009568	chr21	11			11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PRMT2 expression and immune infiltrating cell level correlation result in HIV+ samples
PRMT2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PRMT2 expression and immune infiltrating cell level correlation result in HIV+ samples
PRMT2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).