HIV Target gene Detail Information

> PRKCSH Gene Search Result

Gene Information

Gene Name	PRKCSH
Gene ID	5589
Gene Full Name	protein kinase C substrate 80K-H
Gene Alias	GIIB; PCLD; PLD1; G19P1; PCLD1; PKCSH; AGE-R2; VASAP-60
Transcripts	ENSG00000130175
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P14314
HGNC ID	HGNC:9411
VEGA ID	OTTHUMG00000182029
OMIM ID	177060
String ID	9606.ENSP00000466134
PharmGKB ID	PA33774

Target gene [PRKCSH] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003114	chr19	61	8		69	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PRKCSH expression and immune infiltrating cell level correlation result in HIV+ samples
PRKCSH expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PRKCSH expression and immune infiltrating cell level correlation result in HIV+ samples
PRKCSH expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).