HBV Target gene Detail Information

> PRKCQ Gene Search Result


Gene Information
Gene Name PRKCQ
Gene ID 5588
Gene Full Name protein kinase C theta
Gene Alias PRKCT; nPKC-theta
Transcripts ENSG00000065675
Virus HBV
Gene Type protein coding
HPA Location Info Centriolar satellite;
HPA Protein Class Info Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q04759
HGNC ID HGNC:9410
VEGA ID OTTHUMG00000017623
OMIM ID 600448
String ID 9606.ENSP00000263125
Drugbank ID BE0001385; BE0004895
Drug (Cytoscape Annotation) Bosutinib
PharmGKB ID PA33773
Target gene [PRKCQ] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1018791 chr10 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PRKCQ expression and immune infiltrating cell level correlation result in HBV+ samples
PRKCQ expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).