HBV Target gene Detail Information

> PRKCG Gene Search Result

Gene Information

Gene Name	PRKCG
Gene ID	5582
Gene Full Name	protein kinase C gamma
Gene Alias	PKCC; PKCG; SCA14; PKCI(3); PKCgamma; PKC-gamma
Transcripts	ENSG00000126583
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	P05129
HGNC ID	HGNC:9402
VEGA ID	OTTHUMG00000064846
OMIM ID	176980
String ID	9606.ENSP00000263431
Drugbank ID	BE0004830; BE0009588; BE0004895
PharmGKB ID	PA33766

Target gene [PRKCG] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009494	chr19	15			15	View
1403392	chr19	15			15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PRKCG expression and immune infiltrating cell level correlation result in HBV+ samples
PRKCG expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).