HBV Target gene Detail Information

> PRKCE Gene Search Result

Gene Information

Gene Name	PRKCE
Gene ID	5581
Gene Full Name	protein kinase C epsilon
Gene Alias	PKCE; nPKC-epsilon
Transcripts	ENSG00000171132
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Intermediate filaments;Plasma membrane;Vesicles;
HPA Protein Class Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Gene Function	Suppressor gene & Oncogene
Uniport_ID	Q02156
HGNC ID	HGNC:9401
VEGA ID	OTTHUMG00000128817
OMIM ID	176975
String ID	9606.ENSP00000306124
Drugbank ID	BE0003431; BE0004895
Drug (Cytoscape Annotation)	Ruxolitinib Phosphate
PharmGKB ID	PA33765

Target gene [PRKCE] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002411	chr2	97	118	64	279	View
1002412	chr2	97	118	64	279	View
1002413	chr2	97	118	64	279	View
1002414	chr2	97	118	64	279	View
1002415	chr2	97	118	64	279	View
1002416	chr2	97	118	64	279	View
1002417	chr2	97	118	64	279	View
1004734	chr2	67	2	1	70	View
1005735	chr2	10	33	6	49	View
1008012	chr2	20	3		23	View
1402819	chr2	67	2	1	70	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PRKCE expression and immune infiltrating cell level correlation result in HBV+ samples
PRKCE expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).