HBV Target gene Detail Information

> PRKCB Gene Search Result

Gene Information

Gene Name	PRKCB
Gene ID	5579
Gene Full Name	protein kinase C beta
Gene Alias	PKCB; PRKCB1; PRKCB2; PKCI(2); PKCbeta; PKC-beta
Transcripts	ENSG00000166501
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins
Gene Function	Suppressor gene
Uniport_ID	P05771
HGNC ID	HGNC:9395
VEGA ID	OTTHUMG00000131615
OMIM ID	176970
String ID	9606.ENSP00000305355
Drugbank ID	BE0000872; BE0004895
PharmGKB ID	PA33761

Target gene [PRKCB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007954	chr16	23			23	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PRKCB expression and immune infiltrating cell level correlation result in HBV+ samples
PRKCB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).