HIV Target gene Detail Information

> PRKAR2B Gene Search Result

Gene Information

Gene Name	PRKAR2B
Gene ID	5577
Gene Full Name	protein kinase cAMP-dependent type II regulatory subunit beta
Gene Alias	PRKAR2; RII-BETA
Transcripts	ENSG00000284096
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	P31323
HGNC ID	HGNC:9392
VEGA ID	OTTHUMG00000137418
OMIM ID	176912
String ID	9606.ENSP00000265717
Drugbank ID	BE0004497
PharmGKB ID	PA33758

Target gene [PRKAR2B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005006	chr7	27	9	1	37	View
4008741	chr7	5	9		14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PRKAR2B expression and immune infiltrating cell level correlation result in HIV+ samples
PRKAR2B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).