HIV Target gene Detail Information

> PRKAR2A Gene Search Result

Gene Information

Gene Name	PRKAR2A
Gene ID	5576
Gene Full Name	protein kinase cAMP-dependent type II regulatory subunit alpha
Gene Alias	PKR2; PRKAR2
Transcripts	ENSG00000114302
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	P13861
HGNC ID	HGNC:9391
VEGA ID	OTTHUMG00000133540
OMIM ID	176910
String ID	9606.ENSP00000265563
Drugbank ID	BE0003424
PharmGKB ID	PA33757

Target gene [PRKAR2A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005792	chr3	27	2		29	View
4006060	chr3	27			27	View
4012982	chr3	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PRKAR2A expression and immune infiltrating cell level correlation result in HIV+ samples
PRKAR2A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).