HIV Target gene Detail Information

> PRKAR2A Gene Search Result


Gene Information
Gene Name PRKAR2A
Gene ID 5576
Gene Full Name protein kinase cAMP-dependent type II regulatory subunit alpha
Gene Alias PKR2; PRKAR2
Transcripts ENSG00000114302
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P13861
HGNC ID HGNC:9391
VEGA ID OTTHUMG00000133540
OMIM ID 176910
String ID 9606.ENSP00000265563
Drugbank ID BE0003424
PharmGKB ID PA33757
Target gene [PRKAR2A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4005792 chr3 27 2 29 View
4006060 chr3 27 27 View
4012982 chr3 4 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PRKAR2A expression and immune infiltrating cell level correlation result in HIV+ samples
PRKAR2A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).