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EBV Target gene Detail Information

> PRKAR1B Gene Search Result


Gene Information
Gene Name PRKAR1B
Gene ID 5575
Gene Full Name protein kinase cAMP-dependent type I regulatory subunit beta
Gene Alias PRKAR1
Transcripts ENSG00000188191
Virus EBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID P31321
HGNC ID HGNC:9390
VEGA ID OTTHUMG00000151411
OMIM ID 176911
String ID 9606.ENSP00000385749
PharmGKB ID PA33756
Target gene [PRKAR1B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000035 chr7 412 579 11 1002 View
3300182 chr7 107 54 35 196 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO) Burkitt lymphoma 14 Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO) Burkitt lymphoma 12 Burkitt lymphoma cell line Awia (EBV+)(12)
GSE135644 (GEO) Gastric carcinoma 10 Gastric adenocarcinoma cell line AGS (5), Gastric adenocarcinoma cell line AGS (EBV+)(5)
GSE45919 (GEO) Infectious mononucleosis 24 Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO) Multiple sclerosis 32 Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)
GSE12452 (GEO) Nasopharyngeal carcinoma 41 Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of PRKAR1B expression and immune infiltrating cell level correlation result in EBV+ samples
PRKAR1B expression: Low -> High

> Dataset: GSE100458

HeatMap of cell type fractions in all samples Lollipop of PRKAR1B expression and immune infiltrating cell level correlation result in EBV+ samples
PRKAR1B expression: Low -> High

> Dataset: GSE42867

HeatMap of cell type fractions in all samples Lollipop of PRKAR1B expression and immune infiltrating cell level correlation result in EBV+ samples
PRKAR1B expression: Low -> High

> Dataset: GSE135644

HeatMap of cell type fractions in all samples Lollipop of PRKAR1B expression and immune infiltrating cell level correlation result in EBV+ samples
PRKAR1B expression: Low -> High

> Dataset: GSE45919

HeatMap of cell type fractions in all samples Lollipop of PRKAR1B expression and immune infiltrating cell level correlation result in EBV+ samples
PRKAR1B expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of PRKAR1B expression and immune infiltrating cell level correlation result in EBV+ samples
PRKAR1B expression: Low -> High

> Dataset: GSE58240

HeatMap of cell type fractions in all samples Lollipop of PRKAR1B expression and immune infiltrating cell level correlation result in EBV+ samples
PRKAR1B expression: Low -> High

> Dataset: GSE12452

HeatMap of cell type fractions in all samples Lollipop of PRKAR1B expression and immune infiltrating cell level correlation result in EBV+ samples
PRKAR1B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).