HBV Target gene Detail Information

> PRKACB Gene Search Result

Gene Information

Gene Name	PRKACB
Gene ID	5567
Gene Full Name	protein kinase cAMP-activated catalytic subunit beta
Gene Alias	PKACB; PKA C-beta
Transcripts	ENSG00000142875
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Cytokinetic bridge;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	P22694
HGNC ID	HGNC:9381
VEGA ID	OTTHUMG00000009975
OMIM ID	176892
String ID	9606.ENSP00000359719
Drugbank ID	BE0004475
PharmGKB ID	PA33749

Target gene [PRKACB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000269	chr1	2682	246	327	3255	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PRKACB expression and immune infiltrating cell level correlation result in HBV+ samples
PRKACB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).