HBV Target gene Detail Information

> PRKAB2 Gene Search Result

Gene Information

Gene Name	PRKAB2
Gene ID	5565
Gene Full Name	protein kinase AMP-activated non-catalytic subunit beta 2
Transcripts	ENSG00000131791
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O43741
HGNC ID	HGNC:9379
VEGA ID	OTTHUMG00000014032
OMIM ID	602741
String ID	9606.ENSP00000254101
Drugbank ID	BE0000774; BE0004907
PharmGKB ID	PA33747

Target gene [PRKAB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000209	chr1	2684	801	599	4084	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PRKAB2 expression and immune infiltrating cell level correlation result in HBV+ samples
PRKAB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).