HBV Target gene Detail Information

> PRKAB1 Gene Search Result

Gene Information

Gene Name	PRKAB1
Gene ID	5564
Gene Full Name	protein kinase AMP-activated non-catalytic subunit beta 1
Gene Alias	AMPK; HAMPKb
Transcripts	ENSG00000111725
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	FDA approved drug targets, Predicted intracellular proteins
Uniport_ID	Q9Y478
HGNC ID	HGNC:9378
VEGA ID	OTTHUMG00000168954
OMIM ID	602740
String ID	9606.ENSP00000229328
Drugbank ID	BE0000254; BE0004907
PharmGKB ID	PA33746

Target gene [PRKAB1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005232	chr12	25	6	27	58	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PRKAB1 expression and immune infiltrating cell level correlation result in HBV+ samples
PRKAB1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).