HTLV1 Target gene Detail Information

> PRDM15 Gene Search Result

Gene Information

Gene Name	PRDM15
Gene ID	63977
Gene Full Name	PR/SET domain 15
Gene Alias	PFM15; ZNF298; C21orf83
Transcripts	ENSG00000141956
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	P57071
HGNC ID	HGNC:13999
VEGA ID	OTTHUMG00000086781
OMIM ID	617692
String ID	9606.ENSP00000269844
PharmGKB ID	PA33713

Target gene [PRDM15] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6011328	chr21	23	3	1	27	View
6015401	chr21	11	3		14	View
6020736	chr21	5	1		6	View
6025362	chr21	1	2		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PRDM15 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PRDM15 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PRDM15 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PRDM15 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of PRDM15 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PRDM15 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).