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HTLV1 Target gene Detail Information

> PRDM11 Gene Search Result


Gene Information
Gene Name PRDM11
Gene ID 56981
Gene Full Name PR/SET domain 11
Gene Alias PFM8
Transcripts ENSG00000019485
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q9NQV5
HGNC ID HGNC:13996
VEGA ID OTTHUMG00000166478
OMIM ID 616347
String ID 9606.ENSP00000480626
PharmGKB ID PA33709
Target gene [PRDM11] related to VISs
DVIDChromosomeHMTFBSCASum of Overlapped RecordsDetail
6024837 chr11 3 3 View
Showing 1 to 1 of 1 entries
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Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of PRDM11 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PRDM11 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of PRDM11 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PRDM11 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of PRDM11 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PRDM11 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).