HIV Target gene Detail Information

> PPTC7 Gene Search Result

Gene Information

Gene Name	PPTC7
Gene ID	160760
Gene Full Name	PTC7 protein phosphatase homolog
Gene Alias	TAPP2C; TA-PP2C
Transcripts	ENSG00000196850
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q8NI37
HGNC ID	HGNC:30695
VEGA ID	OTTHUMG00000169529
OMIM ID	609668
String ID	9606.ENSP00000346255
PharmGKB ID	PA143485580

Target gene [PPTC7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000694	chr12	47	150	117	314	View
4002470	chr12	55	33	5	93	View
4005481	chr12	29	3		32	View
4006815	chr12	18	4		22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PPTC7 expression and immune infiltrating cell level correlation result in HIV+ samples
PPTC7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PPTC7 expression and immune infiltrating cell level correlation result in HIV+ samples
PPTC7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).