HIV Target gene Detail Information

> PPP6R2 Gene Search Result


Gene Information
Gene Name PPP6R2
Gene ID 9701
Gene Full Name protein phosphatase 6 regulatory subunit 2
Gene Alias PP6R2; SAPS2; SAP190; KIAA0685
Transcripts ENSG00000100239
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Vesicles;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID O75170
HGNC ID HGNC:19253
VEGA ID OTTHUMG00000150199
OMIM ID 610877
String ID 9606.ENSP00000478417
PharmGKB ID PA165378360
Target gene [PPP6R2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000334 chr22 381 77 71 529 View
4000493 chr22 340 18 69 427 View
4002625 chr22 81 3 2 86 View
4002896 chr22 3 1 72 76 View
4002928 chr22 4 71 75 View
4004102 chr22 8 12 29 49 View
4007207 chr22 20 20 View
4007354 chr22 18 2 20 View
4009253 chr22 8 1 3 12 View
4010215 chr22 6 3 9 View
4010427 chr22 8 1 9 View
4011244 chr22 7 7 View
4011390 chr22 7 7 View
4011391 chr22 7 7 View
4011392 chr22 5 2 7 View
4011656 chr22 4 2 6 View
4011749 chr22 6 6 View
4012814 chr22 3 1 4 View
4013387 chr22 3 3 View
4013478 chr22 3 3 View
4013680 chr22 2 1 3 View
4013681 chr22 3 3 View
4013809 chr22 3 3 View
4013810 chr22 3 3 View
4014452 chr22 1 1 2 View
4014453 chr22 2 2 View
4015666 chr22 1 1 View
4016642 chr22 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PPP6R2 expression and immune infiltrating cell level correlation result in HIV+ samples
PPP6R2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).