HIV Target gene Detail Information

> PPP6R1 Gene Search Result


Gene Information
Gene Name PPP6R1
Gene ID 22870
Gene Full Name protein phosphatase 6 regulatory subunit 1
Gene Alias PP6R1; SAPS1; SAP190; KIAA1115
Transcripts ENSG00000105063
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9UPN7
HGNC ID HGNC:29195
VEGA ID OTTHUMG00000180704
OMIM ID 610875
String ID 9606.ENSP00000414202
PharmGKB ID PA165394108
Target gene [PPP6R1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4006618 chr19 13 10 23 View
4008996 chr19 12 1 13 View
4011518 chr19 6 6 View
4012155 chr19 4 1 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PPP6R1 expression and immune infiltrating cell level correlation result in HIV+ samples
PPP6R1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).