HIV Target gene Detail Information

> PPP6C Gene Search Result

Gene Information

Gene Name	PPP6C
Gene ID	5537
Gene Full Name	protein phosphatase 6 catalytic subunit
Gene Alias	PP6; PP6C
Transcripts	ENSG00000119414
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Uniport_ID	O00743
HGNC ID	HGNC:9323
VEGA ID	OTTHUMG00000020671
OMIM ID	612725
String ID	9606.ENSP00000392147
PharmGKB ID	PA33687

Target gene [PPP6C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007530	chr9	18	1		19	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PPP6C expression and immune infiltrating cell level correlation result in HIV+ samples
PPP6C expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PPP6C expression and immune infiltrating cell level correlation result in HIV+ samples
PPP6C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).