HBV Target gene Detail Information

> PPP4R4 Gene Search Result

Gene Information

Gene Name	PPP4R4
Gene ID	57718
Gene Full Name	protein phosphatase 4 regulatory subunit 4
Gene Alias	PP4R4; CFAP14; KIAA1622
Transcripts	ENSG00000278326
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6NUP7
HGNC ID	HGNC:23788
VEGA ID	OTTHUMG00000190240
OMIM ID	616790
String ID	9606.ENSP00000305924
PharmGKB ID	PA164724938

Target gene [PPP4R4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004322	chr14	67	18		85	View
1404584	chr14	209	71	25	305	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PPP4R4 expression and immune infiltrating cell level correlation result in HBV+ samples
PPP4R4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).