HTLV1 Target gene Detail Information

> PPP4C Gene Search Result


Gene Information
Gene Name PPP4C
Gene ID 5531
Gene Full Name protein phosphatase 4 catalytic subunit
Gene Alias PP4; PPX; PP-X; PP4C; PPH3; PPP4
Transcripts ENSG00000149923
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;Plasma membrane;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID P60510
HGNC ID HGNC:9319
VEGA ID OTTHUMG00000132113
OMIM ID 602035
String ID 9606.ENSP00000279387
PharmGKB ID PA33683
Target gene [PPP4C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6100161 chr16 4038 1917 1159 7114 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of PPP4C expression and immune infiltrating cell level correlation result in HTLV1+ samples
PPP4C expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).