HIV Target gene Detail Information

> PPP3R1 Gene Search Result

Gene Information

Gene Name	PPP3R1
Gene ID	5534
Gene Full Name	protein phosphatase 3 regulatory subunit B, alpha
Gene Alias	CNB; CNB1; CALNB1
Transcripts	ENSG00000221823
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	P63098
HGNC ID	HGNC:9317
VEGA ID	OTTHUMG00000129561
OMIM ID	601302
String ID	9606.ENSP00000234310
Drugbank ID	BE0000358
PharmGKB ID	PA33681

Target gene [PPP3R1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001332	chr2	72	43	62	177	View
4006557	chr2	15	9		24	View
4007914	chr2	17			17	View
4009749	chr2	2	9		11	View
4010862	chr2	5	3		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PPP3R1 expression and immune infiltrating cell level correlation result in HIV+ samples
PPP3R1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PPP3R1 expression and immune infiltrating cell level correlation result in HIV+ samples
PPP3R1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).