HIV Target gene Detail Information

> PPP2R5E Gene Search Result

Gene Information

Gene Name	PPP2R5E
Gene ID	5529
Gene Full Name	protein phosphatase 2 regulatory subunit B'epsilon
Gene Alias	B56E; B56epsilon
Transcripts	ENSG00000154001
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q16537
HGNC ID	HGNC:9313
VEGA ID	OTTHUMG00000140341
OMIM ID	601647
String ID	9606.ENSP00000337641
PharmGKB ID	PA33677

Target gene [PPP2R5E] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000552	chr14	287	58	30	375	View
4004276	chr14	14	32		46	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PPP2R5E expression and immune infiltrating cell level correlation result in HIV+ samples
PPP2R5E expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PPP2R5E expression and immune infiltrating cell level correlation result in HIV+ samples
PPP2R5E expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).