HBV Target gene Detail Information

> PPP2R5C Gene Search Result


Gene Information
Gene Name PPP2R5C
Gene ID 5527
Gene Full Name protein phosphatase 2 regulatory subunit B'gamma
Gene Alias B56G; PR61G; B56gamma
Transcripts ENSG00000078304
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Golgi apparatus;
HPA Protein Class Info Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q13362
HGNC ID HGNC:9311
VEGA ID OTTHUMG00000171597
OMIM ID 601645
String ID 9606.ENSP00000412324
Drugbank ID BE0003749
PharmGKB ID PA33674
Target gene [PPP2R5C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003546 chr14 117 7 1 125 View
1004263 chr14 47 14 26 87 View
1005039 chr14 42 9 12 63 View
1013916 chr14 4 4 View
1013917 chr14 3 1 4 View
1400688 chr14 117 7 1 125 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PPP2R5C expression and immune infiltrating cell level correlation result in HBV+ samples
PPP2R5C expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).