HBV Target gene Detail Information

> PPP2R2C Gene Search Result


Gene Information
Gene Name PPP2R2C
Gene ID 5522
Gene Full Name protein phosphatase 2 regulatory subunit Bgamma
Gene Alias PR52; PR55G; IMYPNO; IMYPNO1; B55gamma; B55-GAMMA
Transcripts ENSG00000074211
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q9Y2T4
HGNC ID HGNC:9306
VEGA ID OTTHUMG00000090445
OMIM ID 605997
String ID 9606.ENSP00000335083
PharmGKB ID PA33670
Target gene [PPP2R2C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002666 chr4 133 76 17 226 View
1004861 chr4 19 39 9 67 View
1006575 chr4 3 24 9 36 View
1010115 chr4 9 4 13 View
1011015 chr4 4 6 10 View
1013664 chr4 4 4 View
1019852 chr4 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PPP2R2C expression and immune infiltrating cell level correlation result in HBV+ samples
PPP2R2C expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).