HBV Target gene Detail Information

> PPP2R2B Gene Search Result


Gene Information
Gene Name PPP2R2B
Gene ID 5521
Gene Full Name protein phosphatase 2 regulatory subunit Bbeta
Gene Alias PR52B; SCA12; B55BETA; PR55BETA; PP2ABBETA; PP2APR55B; PR2ABBETA; PR55-BETA; PP2AB55BETA; PR2AB55BETA; PP2APR55BETA; PR2APR55BETA
Transcripts ENSG00000156475
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q00005
HGNC ID HGNC:9305
VEGA ID OTTHUMG00000163381
OMIM ID 604325
String ID 9606.ENSP00000377936
PharmGKB ID PA33669
Target gene [PPP2R2B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009784 chr5 9 3 2 14 View
1009785 chr5 9 3 2 14 View
1009998 chr5 9 3 2 14 View
1012445 chr5 5 2 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PPP2R2B expression and immune infiltrating cell level correlation result in HBV+ samples
PPP2R2B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).