HBV Target gene Detail Information

> PPP2R2A Gene Search Result


Gene Information
Gene Name PPP2R2A
Gene ID 5520
Gene Full Name protein phosphatase 2 regulatory subunit Balpha
Gene Alias B55A; PR52A; PR55A; B55ALPHA; PR55alpha
Transcripts ENSG00000221914
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID P63151
HGNC ID HGNC:9304
VEGA ID OTTHUMG00000163850
OMIM ID 604941
String ID 9606.ENSP00000325074
Drugbank ID BE0003811
PharmGKB ID PA33668
FDA Approved Drug Olaparib
Target gene [PPP2R2A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1013587 chr8 2 3 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PPP2R2A expression and immune infiltrating cell level correlation result in HBV+ samples
PPP2R2A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).