HBV Target gene Detail Information

> PPP2CB Gene Search Result


Gene Information
Gene Name PPP2CB
Gene ID 5516
Gene Full Name protein phosphatase 2 catalytic subunit beta
Gene Alias PP2CB; PP2Abeta
Transcripts ENSG00000104695
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID P62714
HGNC ID HGNC:9300
VEGA ID OTTHUMG00000163949
OMIM ID 176916
String ID 9606.ENSP00000221138
Drugbank ID BE0002325
PharmGKB ID PA33664
Target gene [PPP2CB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006546 chr8 11 24 2 37 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PPP2CB expression and immune infiltrating cell level correlation result in HBV+ samples
PPP2CB expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).