HIV Target gene Detail Information

> PPP1R7 Gene Search Result

Gene Information

Gene Name	PPP1R7
Gene ID	5510
Gene Full Name	protein phosphatase 1 regulatory subunit 7
Gene Alias	SDS22
Transcripts	ENSG00000115685
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q15435
HGNC ID	HGNC:9295
VEGA ID	OTTHUMG00000133390
OMIM ID	602877
String ID	9606.ENSP00000234038
PharmGKB ID	PA33658

Target gene [PPP1R7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004522	chr2	29	7	7	43	View
4006926	chr2	18	4		22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PPP1R7 expression and immune infiltrating cell level correlation result in HIV+ samples
PPP1R7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PPP1R7 expression and immune infiltrating cell level correlation result in HIV+ samples
PPP1R7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).