HBV Target gene Detail Information

> PPP1R3C Gene Search Result


Gene Information
Gene Name PPP1R3C
Gene ID 5507
Gene Full Name protein phosphatase 1 regulatory subunit 3C
Gene Alias PTG; PPP1R5
Transcripts ENSG00000119938
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9UQK1
HGNC ID HGNC:9293
VEGA ID OTTHUMG00000018745
OMIM ID 602999
String ID 9606.ENSP00000238994
PharmGKB ID PA33653
Target gene [PPP1R3C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000227 chr10 1443 1217 1146 3806 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PPP1R3C expression and immune infiltrating cell level correlation result in HBV+ samples
PPP1R3C expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).